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UGT1A1 and UGT1A3: Decoding the Mysteries of Human Microsomal Enzymes
Enzymes act as crucial signposts in the intricate maze of human metabolism, guiding and accelerating various biochemical reactions. Among these, the UGT1A1 and UGT1A3 enzymes have recently piqued scientific curiosity…
Harnessing Advanced Predictive Models to Propel Drug Metabolism and Pharmacokinetics
The quest for ensuring drug efficacy and safety is perennial in the complex realm of Drug Metabolism and Pharmacokinetics (DMPK). The pathway from drug discovery to development is fraught with uncertainties…
The Role of Drug Metabolism and Pharmacokinetics (DMPK) in Understanding and Combating Antimicrobial Resistance
Drug metabolism is a complex process involving converting drugs into more….
Recent Advances in Drug Metabolism and Pharmacokinetics: Innovation at PharmaJen
At PharmaJen, we are committed to staying at the forefront of Drug Metabolism and Pharmacokinetics (DMPK) research. We aim to drive advancements that revolutionize drug development…
The Role of Generative AI in Predicting Drug Metabolism and Pharmacokinetics
Drug discovery has traditionally been a costly and complex process fraught with significant challenges. An essential part of this process is understanding drug metabolism and pharmacokinetics, crucial determinants of a drug’s safety and effectiveness….
Delving into Ivermectin’s Influence on Bile Acids: A Scientific Exploration
PharmaJen recently published an article titled “Simultaneous determination of seven bile acids to study the effect of ivermectin on their plasma levels in rats by UHPLC–MS/MS” on October 16th, 2023. The purpose of this blog is to provide…
Impact of the latest developments in drug metabolism and pharmacokinetics (DMPK) on Personalized medicine
Drug metabolism and pharmacokinetics (DMPK) is a crucial aspect of personalized medicine…
Artificial Intelligence in Drug Discovery & Development
Artificial intelligence (AI) is increasingly used to assist in the discovery and development of new drugs. The use of AI in drug discovery and development offers many potential benefits, including the ability to analyze large amounts of data,…
Top 10 Applications of Artificial Neural Networks(ANNs) in Model Drug-Drug interaction in the Body
Artificial neural networks (ANNs) are a type of machine learning algorithm inspired by the human….
Review of Open System Pharmacology (OSP) Suite
Open System Pharmacology (OSP) is a suite of software tools that allow users to build and simulate pharmacokinetic-pharmacodynamic (PK-PD) models of drugs and their effects on the human body…
Artificial Intelligence in Drug Metabolism and Pharmacokinetics
Artificial intelligence (AI) has the potential to revolutionize drug metabolism and pharmacokinetics, which are central to the field of pharmacology and play a crucial role in drug development and safety. …
Exploring the Role of Cytochrome P450 Enzymes in Drug Metabolism
Cytochrome P450 enzymes, also known as CYPs, are a copious and varied family of enzymes that serve a vital role in drug metabolism. These enzymes are located in the liver and other organs and are responsible for the biotransformation of a wide range of compounds, …